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Disease model is the broadest and most common way to research and investigate human diseases, in order to better understand the disease process without harming a human. Although the explore process in disease model cannot exactly equivalent to the process in human, as a guide, these researches make a significant contribution to development of many drugs, treatments, and cures for human diseases. As humans’ closest relatives, humans share about 99% of our genome with chimpanzees, while as the most common animal model, humans share about 90% with the mouse. Scientists have been able to take advantage of these similarities in generating experimental and predictive models of human disease.
CD BioSciences has extensive experience and advanced equipment in the services of disease models to ensure your disease models successful and repeatable in order to accelerate your targeted drug discovery project. Our services cover full disease models, including neurological disease models, cardiovascular disease models, immunology and inflammation models, and others.
Nervous system consists of brain, spinal cord, and nerves, the primary function of the nervous system is to control the body. The disorder of nervous system always causes lead to difficulties in swallowing, breathing, speaking, moving, learning, etc. Therefore, treatments of nervous system are crucial for human health. CD BioSciences has rich experience and professional technology on establishing neurological disease models, including but not limited to Parkinson's disease, cerebral stroke, Alzheimer’s disease, Huntington's disease, amyotrophic lateral sclerosis, multiple sclerosis, Batten disease, and others disease models. In addition, we provide customized services on establishing neurological disease models.
Parkinson's disease (PD) is long-term degenerative disorder of the central nervous system that mainly affects the motor system. The most obvious symptoms in the early stages of PD are tremor, rigidity, slowness of movement, and difficulty with walking. Parkinson's disease dementia always occurs in the advanced stages of PD. People over the age of 60 are most likely to develop Parkinson’s disease, of whom about one percent are affected, besides, hundreds of thousands of people died of Parkinson’s disease. CD BioSciences provides various Parkinson's disease models to satisfy different research demands for worldwide clients.
Stroke is the second cause of death worldwide. Although the researches on stroke have gone on for decades, enormous challenges remain in these treatments. The focal cerebral ischemic model of stroke is commonly used to evaluate ischemic injury of the brain. CD BioSciences establishes cerebral stroke models with micro catheter embolization or blood vessel clamping method through-pterion, orbital or supraorbital operation.
Others rare neurological diseases affect the health of tens of thousands of people each year. The researches on these rare neurological diseases are also vital for human health. CD BioSciences provides neurological diseases models according to your experimental requirements.
The essential components of the human cardiovascular system are the heart, blood, and blood vessels. Cardiovascular diseases, as the most common non-communicable disease, kill a lot of people. It includes coronary artery diseases, heart failure, hypertensive heart disease, rheumatic heart disease, cardiomyopathy, abnormal heart rhythms, congenital heart disease, valvular heart disease, carditis, aortic aneurysms, peripheral artery disease, thromboembolic disease, and venous thrombosis. It was reported that 17.9 million people died of cardiovascular diseases annually, which imposes a particularly severe medical burden. More and deeper understanding of the pathogenesis and pathological characteristics of cardiovascular diseases is essential for effective treatment methods or preventive measures. Cardiovascular disease models play a vital role in the research of cardiovascular diseases. CD BioSciences offers various cardiovascular disease models with different ways. Welcome to inquire us the details about establishing various cardiovascular disease models.
Immunology is a kind of biology to study immune system in all organisms. The normal function of immune system is vital for the normal function of the body. Once the disorder of immune system, many diseases occur. There are two main diseases caused by disorders of the immune system. One is immunodeficiency such as, chronic granulomatous disease and primary immune diseases, another is autoimmunity, including systemic lupus erythematosus, rheumatoid arthritis, Hashimoto's disease, and myasthenia gravis, besides, various hypersensitivities also due to immune system disorders.
Immunology is a kind of biology to study immune system in all organisms. The normal function of immune system is vital for the normal function of the body. Once the disorder of immune system, many diseases occur. There are two main diseases caused by disorders of the immune system. One is immunodeficiency such as, chronic granulomatous disease and primary immune diseases, another is autoimmunity, including systemic lupus erythematosus, rheumatoid arthritis, Hashimoto's disease, and myasthenia gravis, besides, various hypersensitivities also due to immune system disorders.
Available Model Animals
Rodents, zebrafish, rabbits, dogs, cats, pigs, tree shrews, monkey, non-human primates (NHPs) Non-mammals.
Advantages of CD BioSciences
Extensive Experience, Professional Technicians, Advanced Equipment, Customized Services.
